4-氯-5H-吡咯[3,2-D]嘧啶-7-甲酸 - Names and Identifiers
Name | 4-Chloro-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylic acid
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Synonyms | LogP 4-Chloro-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylic acid 4-chloro-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylic acid 5H-pyrrolo[3,2-d]pyrimidine-7-carboxylic acid, 4-chloro- Lithium 4-chloro-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylate
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CAS | 853058-43-2 1019056-31-5
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InChI | InChI=1/C7H4ClN3O2/c8-6-5-4(10-2-11-6)3(1-9-5)7(12)13/h1-2,9H,(H,12,13) |
4-氯-5H-吡咯[3,2-D]嘧啶-7-甲酸 - Physico-chemical Properties
Molecular Formula | C7H4ClN3O2
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Molar Mass | 197.58 |
Density | 1.751g/cm3 |
Boling Point | 494.5°C at 760 mmHg |
Flash Point | 252.9°C |
Vapor Presure | 1.35E-10mmHg at 25°C |
Storage Condition | 2-8℃ |
Refractive Index | 1.762 |
4-氯-5H-吡咯[3,2-D]嘧啶-7-甲酸 - Introduction
4-Chloro-5H-pyramid [3,2-d]pyrimidine-7-carboxylic acid is an organic compound with the following properties:
1. Appearance: Colorless crystalline solid.
2. molecular formula: C8H4ClN3O2.
3. Molecular weight: 209.59g/mol.
4. Melting point: about 180-182°C.
5. Solubility: Soluble in some organic solvents, such as dichloromethane and dimethyl sulfoxide.
The main use of the compound is as an intermediate in the field of medicine. It can be used to synthesize various bioactive molecules, such as drugs and pesticides. In addition, it can also be used for catalytic reactions in organic synthesis and the construction of heterocyclic compounds.
The method of preparing 4-Chloro-5H-cryrolo [3,2-d]pyrimidine-7-carboxylic acid can be carried out by the following steps:
1. taking pyrrolo [3,2-d] pyrimidine as raw material.
2. under appropriate conditions, it and cuprous chloride (CuCl) as chlorinating agent in chlorinated solvent reaction.
3. 4-Chloro-5H-pyrrolo [3,2-d] pyrimidine was obtained.
4. 4-Chloro-5H-pyrrolo[3,2-d]pyrimidine is further reacted with an organic carboxylic acid to give 4-Chloro-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylic acid.
Regarding safety information, the specific risk of 4-Chloro-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylic acid is not known. However, since it is a chemical, the following should be noted when handling:
1. Avoid inhalation of dust and contact with skin, eyes and mucous membranes.
2. Wear appropriate protective glasses, gloves and laboratory coats during operation.
3. operation should be carried out in a well-ventilated place.
4. avoid contact with strong oxidants and strong acids.
If necessary, please operate under the guidance of specialized laboratory personnel and follow relevant safety operating procedures.
Last Update:2024-04-09 21:04:16